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Science of SEM

This section focuses on the research completed to develop the SEM assessment technology foundational science and mode of operation. Including how SEM assessment technology identifies increased risk of PI/U and how to treat a high SEM (∆) delta as a stage/category 1 PI/U to prevent them from further deterioration.

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Evaluating the Sensitivity, Specificity and Clinical Utility of Algorithms of Spatial Variation in Sub-Epidermal Moisture (SEM) for the Diagnosis of Deep and Early-Stage Pressure-Induced Tissue Damage.

Gershon, S., Okonkwo, H. 2021. Journal of Wound Care

Aim: To evaluate the ability of an objective test, the SEM, to discriminate between subjects with confirmed PI/U with intact skin versus those with no pressure damage.

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Clinical Profile of the SEM Scanner – Modernizing Pressure Injury Care Pathways Using Sub-Epidermal Moisture (SEM) Scanning.

Bryant, R. A. et al. 2021. Expert Review of Medical Devices

Aim: This is a comprehensive review of SEM technology from a device, safety and efficacy perspective; while it does not add new data for the first time this review brings together all the relevant data into one publication.

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Sub-Epidermal Moisture Measurement and Targeted SSKIN Bundle Interventions, a Winning Combination for the Treatment of Early Pressure Ulcer Development.

Byrne, S. et al. 2022. International Wound Journal

Aim: This study aimed to investigate the impact of sub-epidermal moisture (SEM) measurement and targeted PI/U prevention, versus visual skin assessment and usual care, on mean SEM delta scores and early PI/U development in acute hospital patients.

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Sub-Epidermal Moisture Versus Traditional and Visual Skin Assessments to Assess Pressure Ulcer Risk in Surgery Patients.

Martins de Oliveira, A. L. et al. 2022. Journal of Wound Care

Aim: To compare the predictive ability of sub-epidermal moisture (SEM) measurement versus traditional risk assessment and visual skin assessment (VSA) as means of detecting early PI/U damage development among adults undergoing surgery.


Click here to access our extensive SEM assessment technology bibliography

If you would like to discuss any of the clinical, health economic or real-world evidence on the website or would like further information on them the team would be happy to assist. Please contact us at: [email protected]

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